Renin-Angiotensin System and Kidney Function: Mechanisms, Insights, and Implications
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Moderator(s): Jordana Cohen, Mohammad Saleem

Presentation(s):
  • Fate of Renin Cells in Health and Disease - Roberto Ariel Gomez
  • Renin Control by Mechanosensors: Role of PIEZO2 - Rose Hill
  • Angiotensin-Converting Enzyme 2 and Its Role in Kidney Function and Diseases - Daniel Batlle
  • Angiotensin-Converting Enzyme 2 in Hypertension and Diabetic Kidney Disease - Susan Gurley
Meta Tag
Date 11/6/2025
Pathway 1 Hypertension and Cardiorenal Disorders
Session ID 507274
Keywords
renin–angiotensin system
juxtaglomerular (JG) cells
renin cell plasticity
vascular smooth muscle lineage
RAS blockade
angiotensin receptor blockers (ARBs)
concentric arteriolar hypertrophy
periglomerular fibrosis
kidney hyperinnervation
nerve growth factor (NGF)
Piezo2 mechanosensitive ion channel
intracellular calcium oscillations
ACE2 activity
Ang-(1–7) Mas receptor signaling
recombinant soluble ACE2 therapy